Language

CAS No.110797-35-8|NALPHA-FMOC-L-SERINE TERT-BUTYL ESTER

CAS No.110797-35-8|NALPHA-FMOC-L-SERINE TERT-BUTYL ESTER

Name:NALPHA-FMOC-L-SERINE TERT-BUTYL ESTER CAS No.110797-35-8 MF:C22H25NO5 MW:383.44 Purity:98% Package: 1g,5g,25g,100g,500g,1kg,5kg Worldwide Delivery

Categories：

Biochemicals

Email：sale06@alfachem.cn

Inquiry

Chat Now

Product introduction

Introduction and application of CAS No. 110797-35-8 | NALPHA-FMOC-L-SERINE TERT-BUTYL ESTER

Synonyms:N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-L-SERINEALPHA-T-BUTYLESTER;

NALPHA-[(9H-FLUOREN-9-YLMETHOXY)CARBONYL]-L-SERINETERT-BUTYLESTER;

NALPHA-FMOC-L-SERINETERT-BUTYLESTER;

-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-serinetert-ButylEster;

Specification:

ITEMS	SPECIFICATION
CAS	110797-35-8
MF	C22H25NO5
MW	383.44
Melting point	127 °C
Boiling point	588.4±45.0 °C
Density	1.216±0.06 g/cm3
Acidity coefficient	10.07±0.46
Color	white to orange to green
Solubility	Soluble in chloroform
Form	powder crystal
Storage condition	Sealed in dry,2-8°C

Application:

(9-Fluorenmethoxycarbonyl)-L-serine tert-butyl ester is an important starting reactant in peptide synthesis, and it has been widely used in peptide synthesis.

Preparation:

Add L-serine tert-butyl ester into the round bottom flask, add 10% sodium carbonate aqueous solution and stir to dissolve, then add dioxane, and dissolve 10% 9-fluorenethoxycarbonyl chloride in dioxane under ice bath The solution was slowly added dropwise into the reaction solution. After the dropwise addition was completed, react in an ice bath for 2 hours, and then react at room temperature for 8 hours. Add water to dilute, and extract 4 times with diethyl ether. The water layer was placed in an ice bath and diluted with concentrated hydrochloric acid. Adjust the pH value until the Congo red test paper becomes blue, place it in the refrigerator overnight, and extract the white precipitate with ethyl acetate. The combined organic liquids are washed with water, and the organic layer is dried with anhydrous magnesium sulfate and drained to obtain the product N-(9 -Fluorenmethoxycarbonyl)-L-serine tert-butyl ester.

Package and transportation :

Package: 1g,5g,25g,100g,500g,1kg,5kg

Transportation: by courier/ by air/ by sea

Key words: